Response to Comment on "Evidence for Positive Epistasis in HIV-1"
نویسندگان
چکیده
منابع مشابه
Comment on "Evidence for positive epistasis in HIV-1".
Bonhoeffer et al. (Reports, 26 November 2004, p. 1547) presented evidence for positive epistasis in a clinical data set of HIV-1 mutants and corresponding fitness values. We demonstrate that biases in the original and simulated data sets may lead to erroneous evidence for epistasis. More rigorous statistical tests must be used to account for such biases before one can infer epistasis.
متن کاملResponse to Comment on "100% Accuracy In
This copy is for your personal, non-commercial use only.
متن کاملAuthor Response to Comment on "Aluminum Phosphide Poisoning: A Case Series in North Iran"
Dear Editor; I wish to thank the authors for their careful comment (1), on our short report entitled “Aluminum Phosphide Poisoning: A Case Series in North Iran” (2). Unfortunately, as we were excited to display the findings of our series, some facts were missed from the methods of the article. The results presented in our series was collected from eight patients with definitive aluminum phosp...
متن کاملLife expectancy of HIV-1-positive individuals approaches normal conditional on response to antiretroviral therapy: UK Collaborative HIV Cohort Study
Life expectancies (LEs) of patients in UK Collaborative HIV Cohort (UK CHIC) stratified by CD4 count at start of antiretroviral therapy (ART) have been estimated [1] but not gains in years of life in response to ART.We estimated LE associated with attained CD4 count and viral suppression at different durations of ART. Patients in UK CHIC aged 20 years who started ART in 2000 to 2008 (excluding ...
متن کاملResponse to Comment on “Positive Selection of Tyrosine Loss in Metazoan Evolution”
clicking here. colleagues, clients, or customers by , you can order high-quality copies for your If you wish to distribute this article to others here. following the guidelines can be obtained by Permission to republish or repurpose articles or portions of articles ): September 16, 2012 www.sciencemag.org (this information is current as of The following resources related to this article are a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2006
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1110994